Fabrice Kebour started his career in New York. For over twenty years, his work has been presented on the world's major stages: the Comédie-Française, the Paris Opera, the Vienna State Opera, the Bregenz Festival, La Scala in Milan, the Mariinsky Theatre in St. Petersburg, and La Monnaie in Brussels.

He designed the lighting for Giorgio Barberio Corsetti's productions of Un chapeau de paille d'Italie at the Comédie-Française, Macbeth and Turandot at La Scala, and Don Carlo at the Mariinsky Theatre. He has also collaborated with Sir David Pountney for many years, most notably on La Forza del Destino at the Vienna State Opera, The Magic Flute on Lake Bregenz, and Philip Glass's world premiere of Spuren der Verirrten, inaugurating the new opera house in Linz.

In 2011, the Prague Quadriennale invited him to present his work in the retrospective Light Speaks, alongside designers who have shaped their generation. He has also been nominated for the Molière Award for Best Lighting Designer in 2005, 2009, and 2011, and for the Wales Theatre Awards in 2015.

Previous projects include Il Viaggio, Dante at the Festival d'Aix-en-Provence, directed by Claus Guth, Triptych for the Salzburg Festival, directed by Christof Loy, Ring for the Lyric Opera of Chicago, directed by Sir David Pountney, and Hélène d'Égypte for La Scala, directed by Sven-Eric Bechtolf.

More recently, he has designed the lighting for West Side Story at the Théâtre du Châtelet, La Passagère and La Voix humaine in Madrid, La Fiamma at the Deutsche Oper Berlin, Ariodante at the Opéra national du Rhin, and Penderecki's Le Masque noir in Warsaw.

At the Paris Opera: Faust, 2011; La Bohème, 2017; Bérénice, 2018