After completing university studies in Bergamo and Bologna, Giuseppe Frigeni continued his study of contemporary dance in Paris with Françoise and Dominique Dupuy, Carolyn Carlson, David Gordon, Steve Paxton, Lucinda Childs, and José Montalvo.

He has worked as a choreographer with Patrice Chéreau (Don Giovanni, Wozzeck), Peter Stein (Wozzeck, Libussa), Klaus Michael Grüber (Tristan and Isolde, Otello, La Traviata), Luca Ronconi (Don Giovanni), and created the lighting for Dominique Dupuy and Maria Donata D'Urso.

In 1988, he met Robert Wilson, with whom he collaborated as a choreographer and co-director on numerous events (video projects, installations, theater, and opera performances).

Since 1999, he has directed, designed, and lit his own productions: Macbeth (Opera Zuid in Maastricht, Opéra de Bordeaux), Der Jasager by Kurt Weill (Corum in Montpellier), Turandot (Modena, Ferrara, Piacenza, then in Tenerife, Bergamo, Brescia, Cremona, Como, Pavia, and Parma), Saint François d’Assise (Ruhr Triennale, Teatro Real in Madrid), Lohengrin (Opéra de Bordeaux), Le Fou by Landowski (Théâtre Mogador), Wet Snow by Jan van de Putte (Nationale Reisopera, Holland Festival, November Festival), Fidelio (Bordeaux, Cardiff), Passion by Pascal Dusapin (Festival d’Aix-en-Provence, Strasbourg, Luxembourg), La Traviata (Stadttheater in Saint Gallen), Partenope (Teatro Comunale in Ferrara), I’m Her Mouth by Jan van de Putte (Muziekgebouw, Amsterdam), An Enlightened Disciple of Darkness by Dominy Clements (Noblessner, Tallinn Festival), Tristan and Isolde (Opéra de Bordeaux), Back into Nothingness by Nuria Gimenez & Laure Gauthier (2018 Biennale in Villeurbanne, Archipel Festival in Geneva). In 2024, the production of Turandot was revived on tour in Modena, Piacenza, Rimini, and Ravenna by Marina Frigeni.

At the Paris Opera (with Robert Wilson): Le Martyre de Saint-Sébastien, 1988; The Magic Flute, 1991; Madama Butterfly, 1993; Pelléas et Mélisande, 1997; Die Frau ohne Schatten, 2002; The Coronation of Poppea, 2014.